On 2026-06-18, OpenAI published two health stories: a consumer ChatGPT product/evaluation update built on GPT-5.5 Instant that OpenAI reports as rated higher than physician-written responses on a 3,500-response physician panel and a 71% drop in flagged factuality issues on production health traffic over the last two months; and a peer-reviewed NEJM AI study in which OpenAI o3 Deep Research reanalyzed 376 previously unsolved rare-disease cases at Boston Children's Hospital's Manton Center and surfaced candidate diagnoses for 18 cases (4.8% additional yield) after expert ACMG/AMP review and CLIA-certified confirmation — 7 of 18 were rediscoveries of diagnoses already in public databases. Two stories in one day, two separate artifacts, with a load-bearing clinical boundary: the model did not diagnose any patient, and the retrospective study was on heterogeneous cohorts with unblinded reviewers.
OpenAI ships ChatGPT health; o3 re-solves 4.8% of rare